GrippeAllemagneV4, Main, Exploration, bibRecord, 000107

Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.

Identifieur interne : 000107 ( Main/Exploration ); précédent : 000106; suivant : 000108

Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.

Auteurs : Jennifer Haas [Allemagne] ; Sebastian Braun [Allemagne] ; Peter Wutzler [Allemagne]

Source :

The European journal of health economics : HEPAC : health economics in prevention and care [ 1618-7601 ] ; 2016.

RBID : pubmed:26143025

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Allemagne (épidémiologie), Antibactériens (usage thérapeutique), Antibactériens (économie), Antitussifs (usage thérapeutique), Antitussifs (économie), Bases de données factuelles (MeSH), Coûts des soins de santé (statistiques et données numériques), Coûts hospitaliers (MeSH), Coûts indirects de la maladie (MeSH), Demande de remboursement d'assurance (MeSH), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Femelle (MeSH), Grippe humaine (prévention et contrôle), Grippe humaine (traitement médicamenteux), Grippe humaine (économie), Grippe humaine (épidémiologie), Hospitalisation (économie), Humains (MeSH), Mâle (MeSH), Nourrisson (MeSH), Otite moyenne (économie), Otite moyenne (épidémiologie), Pneumopathie infectieuse (économie), Pneumopathie infectieuse (épidémiologie), Répartition par âge (MeSH), Saisons (MeSH), Vaccins antigrippaux (usage thérapeutique), Études rétrospectives (MeSH).
MESH :
- prévention et contrôle : Grippe humaine.
- statistiques et données numériques : Coûts des soins de santé.
- traitement médicamenteux : Grippe humaine.
- usage thérapeutique : Antibactériens, Antitussifs, Vaccins antigrippaux.
- économie : Antibactériens, Antitussifs, Grippe humaine, Hospitalisation, Otite moyenne, Pneumopathie infectieuse.
- épidémiologie : Allemagne, Grippe humaine, Otite moyenne, Pneumopathie infectieuse.
- Adolescent, Adulte, Adulte d'âge moyen, Bases de données factuelles, Coûts hospitaliers, Coûts indirects de la maladie, Demande de remboursement d'assurance, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Mâle, Nourrisson, Répartition par âge, Saisons, Études rétrospectives.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Age Distribution (MeSH), Anti-Bacterial Agents (economics), Anti-Bacterial Agents (therapeutic use), Antitussive Agents (economics), Antitussive Agents (therapeutic use), Child (MeSH), Child, Preschool (MeSH), Cost of Illness (MeSH), Databases, Factual (MeSH), Female (MeSH), Germany (epidemiology), Health Care Costs (statistics & numerical data), Hospital Costs (MeSH), Hospitalization (economics), Humans (MeSH), Infant (MeSH), Influenza Vaccines (therapeutic use), Influenza, Human (drug therapy), Influenza, Human (economics), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Insurance Claim Reporting (MeSH), Male (MeSH), Middle Aged (MeSH), Otitis Media (economics), Otitis Media (epidemiology), Pneumonia (economics), Pneumonia (epidemiology), Retrospective Studies (MeSH), Seasons (MeSH).
MESH :
- chemical , economics : Anti-Bacterial Agents, Antitussive Agents.
- chemical , therapeutic use : Anti-Bacterial Agents, Antitussive Agents, Influenza Vaccines.
- drug therapy : Influenza, Human.
- economics : Hospitalization, Influenza, Human, Otitis Media, Pneumonia.
- epidemiology : Germany, Influenza, Human, Otitis Media, Pneumonia.
- prevention & control : Influenza, Human.
- statistics & numerical data : Health Care Costs.
- Adolescent, Adult, Age Distribution, Child, Child, Preschool, Cost of Illness, Databases, Factual, Female, Hospital Costs, Humans, Infant, Insurance Claim Reporting, Male, Middle Aged, Retrospective Studies, Seasons.

Abstract

OBJECTIVE

Seasonal influenza occurs in annual epidemics. The virus can cause severe illness and concomitant diseases with the highest risk for children, the elderly, and individuals with disease dispositions. The study objective is to assess the influenza burden in Germany.

METHODS

This retrospective claims data analysis used the Health Risk Institute research database containing anonymized data of 4 million individuals. The study period comprised the influenza season 2012/2013 in which patients with documented influenza were identified. Disease frequency rates were calculated for a population with disease dispositions and a population not at high risk. Disease burden was assessed based on health-services utilization during the influenza season. Vaccine rates were calculated by identifying vaccinations.

RESULTS

We observed 65,826 patients with influenza, resulting in 1,160,646 documented influenza cases after extrapolation. Overall, otitis media and pneumonia was higher in the influenza-infected population compared to the non-influenza-infected population and especially high in children. Hospitalization cost amounted to €87,202,485 with a mean stay of 7 days, and total outpatient costs were €14,947,976. Vaccination rates were <4 % for children and 37 % for patients aged >60.

CONCLUSIONS

Seasonal influenza can cause severe outcomes with hospitalizations and excess costs. Especially influenza-infected children are affected by concomitant diseases with higher disease burden. Furthermore, documented vaccination rates are quite low.

DOI: 10.1007/s10198-015-0708-7
PubMed: 26143025
PubMed Central: PMC4899503

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000128
to stream Main, to step Curation: 000128

Le document en format XML

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<term>Adult (MeSH)</term>
<term>Age Distribution (MeSH)</term>
<term>Anti-Bacterial Agents (economics)</term>
<term>Anti-Bacterial Agents (therapeutic use)</term>
<term>Antitussive Agents (economics)</term>
<term>Antitussive Agents (therapeutic use)</term>
<term>Child (MeSH)</term>
<term>Child, Preschool (MeSH)</term>
<term>Cost of Illness (MeSH)</term>
<term>Databases, Factual (MeSH)</term>
<term>Female (MeSH)</term>
<term>Germany (epidemiology)</term>
<term>Health Care Costs (statistics & numerical data)</term>
<term>Hospital Costs (MeSH)</term>
<term>Hospitalization (economics)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
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<term>Influenza, Human (drug therapy)</term>
<term>Influenza, Human (economics)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (prevention & control)</term>
<term>Insurance Claim Reporting (MeSH)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Otitis Media (economics)</term>
<term>Otitis Media (epidemiology)</term>
<term>Pneumonia (economics)</term>
<term>Pneumonia (epidemiology)</term>
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<term>Antibactériens (économie)</term>
<term>Antitussifs (usage thérapeutique)</term>
<term>Antitussifs (économie)</term>
<term>Bases de données factuelles (MeSH)</term>
<term>Coûts des soins de santé (statistiques et données numériques)</term>
<term>Coûts hospitaliers (MeSH)</term>
<term>Coûts indirects de la maladie (MeSH)</term>
<term>Demande de remboursement d'assurance (MeSH)</term>
<term>Enfant (MeSH)</term>
<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (prévention et contrôle)</term>
<term>Grippe humaine (traitement médicamenteux)</term>
<term>Grippe humaine (économie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Hospitalisation (économie)</term>
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<term>Mâle (MeSH)</term>
<term>Nourrisson (MeSH)</term>
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<term>Pneumopathie infectieuse (épidémiologie)</term>
<term>Répartition par âge (MeSH)</term>
<term>Saisons (MeSH)</term>
<term>Vaccins antigrippaux (usage thérapeutique)</term>
<term>Études rétrospectives (MeSH)</term>
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<term>Antitussive Agents</term>
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<term>Grippe humaine</term>
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<term>Grippe humaine</term>
<term>Otite moyenne</term>
<term>Pneumopathie infectieuse</term>
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<term>Adult</term>
<term>Age Distribution</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Cost of Illness</term>
<term>Databases, Factual</term>
<term>Female</term>
<term>Hospital Costs</term>
<term>Humans</term>
<term>Infant</term>
<term>Insurance Claim Reporting</term>
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<term>Retrospective Studies</term>
<term>Seasons</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bases de données factuelles</term>
<term>Coûts hospitaliers</term>
<term>Coûts indirects de la maladie</term>
<term>Demande de remboursement d'assurance</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson</term>
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<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b>
</p>
<p>Seasonal influenza occurs in annual epidemics. The virus can cause severe illness and concomitant diseases with the highest risk for children, the elderly, and individuals with disease dispositions. The study objective is to assess the influenza burden in Germany.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>This retrospective claims data analysis used the Health Risk Institute research database containing anonymized data of 4 million individuals. The study period comprised the influenza season 2012/2013 in which patients with documented influenza were identified. Disease frequency rates were calculated for a population with disease dispositions and a population not at high risk. Disease burden was assessed based on health-services utilization during the influenza season. Vaccine rates were calculated by identifying vaccinations.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>We observed 65,826 patients with influenza, resulting in 1,160,646 documented influenza cases after extrapolation. Overall, otitis media and pneumonia was higher in the influenza-infected population compared to the non-influenza-infected population and especially high in children. Hospitalization cost amounted to €87,202,485 with a mean stay of 7 days, and total outpatient costs were €14,947,976. Vaccination rates were <4 % for children and 37 % for patients aged >60.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Seasonal influenza can cause severe outcomes with hospitalizations and excess costs. Especially influenza-infected children are affected by concomitant diseases with higher disease burden. Furthermore, documented vaccination rates are quite low.</p>
</div>
</front>
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<DateCompleted><Year>2017</Year>
<Month>05</Month>
<Day>19</Day>
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<Month>11</Month>
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<ArticleTitle>Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.</ArticleTitle>
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<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Seasonal influenza occurs in annual epidemics. The virus can cause severe illness and concomitant diseases with the highest risk for children, the elderly, and individuals with disease dispositions. The study objective is to assess the influenza burden in Germany.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">This retrospective claims data analysis used the Health Risk Institute research database containing anonymized data of 4 million individuals. The study period comprised the influenza season 2012/2013 in which patients with documented influenza were identified. Disease frequency rates were calculated for a population with disease dispositions and a population not at high risk. Disease burden was assessed based on health-services utilization during the influenza season. Vaccine rates were calculated by identifying vaccinations.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">We observed 65,826 patients with influenza, resulting in 1,160,646 documented influenza cases after extrapolation. Overall, otitis media and pneumonia was higher in the influenza-infected population compared to the non-influenza-infected population and especially high in children. Hospitalization cost amounted to €87,202,485 with a mean stay of 7 days, and total outpatient costs were €14,947,976. Vaccination rates were <4 % for children and 37 % for patients aged >60.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Seasonal influenza can cause severe outcomes with hospitalizations and excess costs. Especially influenza-infected children are affected by concomitant diseases with higher disease burden. Furthermore, documented vaccination rates are quite low.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Haas</LastName>
<ForeName>Jennifer</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Xcenda GmbH, Lange Laube 31, 30159, Hannover, Germany. jennifer.haas@xcenda.de.</Affiliation>
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<ForeName>Sebastian</ForeName>
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<AffiliationInfo><Affiliation>Xcenda GmbH, Lange Laube 31, 30159, Hannover, Germany.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Wutzler</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Institute of Virology and Antiviral Therapy, Jena University Hospital, Friedrich-Schiller University, Hans-Knöll-Str. 2, 07745, Jena, Germany.</Affiliation>
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<affiliations><list><country><li>Allemagne</li>
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Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.

Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.

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